Ameloblastic carcinoma
Ameloblastic Carcinoma
Ameloblastic carcinoma (pronunciation: a-melo-blastic car-cin-o-ma) is a rare form of odontogenic tumor that originates from the odontogenic epithelium, the tissue responsible for tooth development.
Etymology
The term "ameloblastic" is derived from "ameloblast", which refers to the cells that produce enamel during tooth development. "Carcinoma" is a term used to describe a cancer that starts in the cells that make up the skin or the tissue lining organs.
Definition
Ameloblastic carcinoma is a rare, aggressive malignant tumor that combines the histological features of ameloblastoma with cytological atypia, even in the absence of metastases. It can occur in either the maxilla or mandible, but it is more common in the mandible.
Symptoms
Symptoms of ameloblastic carcinoma may include pain, swelling, and the presence of a hard mass. It may also cause loose teeth, difficulty opening the mouth, and numbness in the lower lip.
Diagnosis
Diagnosis of ameloblastic carcinoma is typically made through a combination of clinical examination, imaging studies such as CT scans or MRI, and histopathological examination of a biopsy specimen.
Treatment
Treatment typically involves surgical removal of the tumor, often followed by radiotherapy. Due to the aggressive nature of the tumor, a wide surgical margin is often required.
Prognosis
The prognosis for ameloblastic carcinoma is generally poor due to its aggressive nature and tendency to recur. The 5-year survival rate is approximately 50%.
Related Terms
External links
- Medical encyclopedia article on Ameloblastic carcinoma
- Wikipedia's article - Ameloblastic carcinoma
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