Alkylating antineoplastic agent
Alkylating Antineoplastic Agent
Alkylating antineoplastic agents are a class of chemotherapeutic drugs used in the treatment of cancer. These agents work by adding an alkyl group to the guanine base of the DNA molecule, preventing the strands of the DNA from separating, thereby inhibiting DNA replication and RNA transcription.
Pronunciation
Alkylating antineoplastic agent: /ˈæl.kɪ.leɪ.tɪŋ æn.tiː.njuːˈplæs.tɪk ˈeɪ.dʒənt/
Etymology
The term "alkylating" is derived from the word "alkyl", which is a type of chemical group. The term "antineoplastic" comes from the Greek words "anti-", meaning against, and "neoplasia", meaning new growth. The term "agent" is used in the sense of a substance that brings about a certain effect.
Related Terms
- Cyclophosphamide: A type of alkylating antineoplastic agent.
- Cisplatin: Another type of alkylating antineoplastic agent.
- Chemotherapy: The use of drugs to treat diseases such as cancer.
- DNA replication: The process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules.
- RNA transcription: The process by which the information in a strand of DNA is copied into a new molecule of messenger RNA (mRNA).
See Also
External links
- Medical encyclopedia article on Alkylating antineoplastic agent
- Wikipedia's article - Alkylating antineoplastic agent
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