Alkaline tide refers to a condition, normally encountered after eating a meal, where during the production of HCl by parietal cells in the stomach, the parietal cells also secrete bicarbonate ions across their basolateral membranes and into the interstitial fluid, causing a temporary increase in pH.
During hydrochloric acid secretion in the stomach, the gastric parietal cells extract chloride anions, carbon dioxide, water and sodium cations from the blood plasma and in turn release bicarbonate back into the plasma after forming it from carbon dioxide and water constituents. This is to maintain the plasma's electrical balance, as the chloride anions have been extracted. The bicarbonate content causes the venous blood leaving the stomach to be more alkaline than the arterial blood delivered to it.
Post-prandial (i.e., after a meal) alkaline tide lasts until the acids in food absorbed in the small intestine reunite with the bicarbonate that was produced when the food was in the stomach. Thus, alkaline tide is self-limited and normally lasts less than two hours.
A more pronounced alkaline tide results from vomiting, which stimulates hyperactivity of gastric parietal cells to replace lost stomach acid (verification needed). Thus, protracted vomiting can result in metabolic alkalosis.
- Taton DF, Hamar D, Lewis LD. Evaluation of ammonium chloride as a urinary acidifier in the cat. Journal of the American Veterinary Medical Association 1984; 184: 433-436.
- McGavin, MD., Zachary, JF. Pathologic Basis of Veterinary Disease, Fourth Edition, Mosby, 2007, pp. 680-686.
W8MD weight loss, sleep and medspa centers
King of Prussia
Other weight loss blogs
W8MD's tele-weight loss - Call (718)946-5500 (NY, NJ) or (215)676-2334 for PA.
I would most definitely recommend to go to here. They are very nice helpful and know what they are doing and talking about, I can see that the doctor has experience for sure. - A patient.
|This cardiovascular system article is a stub. You can help WikiMD by expanding it.|
|This human digestive system article is a stub. You can help WikiMD by expanding it.|