Alclometasone dipropionate

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Alclometasone dipropionate (pronounced al-kloh-MET-uh-sone dye-PROH-pee-oh-nate) is a synthetic corticosteroid used primarily in the treatment of various skin conditions. It is marketed under the brand name Aclovate among others.

Etymology

The name Alclometasone dipropionate is derived from its chemical structure. The prefix Alclo is derived from the chemical group alcohol, and metasone is a common suffix for corticosteroids. Dipropionate refers to the presence of two propionate groups in the molecule.

Pharmacology

Alclometasone dipropionate is a glucocorticoid receptor agonist. It works by reducing inflammation and suppressing the immune response in the skin. This helps to reduce symptoms such as redness, itching, and swelling associated with skin conditions.

Indications

Alclometasone dipropionate is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, such as eczema, psoriasis, and contact dermatitis.

Side Effects

Possible side effects of Alclometasone dipropionate include skin irritation, burning, itching, dryness, and hypopigmentation. Prolonged use may lead to skin thinning and adrenal suppression.

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