Adie syndrome

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Adie syndrome

Adie syndrome (Template:IPA-en), also known as Adie's Pupil or Adie's Tonic Pupil, is a neurological disorder characterized by a tonically dilated pupil that reacts slowly to light but shows a more definite response to accommodation (i.e., it contracts more when looking at a near object).

Etymology

The syndrome is named after the British neurologist William John Adie, who first described it in 1931.

Symptoms

The main symptom of Adie syndrome is the presence of one or more pupils that react abnormally to light. Other symptoms may include loss of deep tendon reflexes, especially in the Achilles tendon, and hyporeflexia. Some patients may also experience hyperhidrosis (excessive sweating), orthostatic hypotension (a drop in blood pressure when standing up), and gastrointestinal problems.

Causes

The exact cause of Adie syndrome is unknown, but it is thought to be due to damage to the postganglionic fibers of the parasympathetic innervation of the eye, usually by a viral or bacterial infection that causes inflammation.

Diagnosis

Diagnosis of Adie syndrome is primarily based on clinical findings. A detailed eye examination, including the use of a slit lamp, can reveal the characteristic tonic pupil. Additional tests may include a tendon reflex examination and a sweat test to check for hyperhidrosis.

Treatment

Treatment for Adie syndrome is usually symptomatic and may include the use of glasses or contact lenses to correct any associated vision problems. In some cases, medications such as pilocarpine may be used to constrict the pupil and improve light reaction.

See also

References

External links

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