Addisonian

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Addisonian

Addisonian (/ædɪˈsoʊniən/), also known as Addison's disease, is a rare, chronic endocrine disorder in which the adrenal glands do not produce sufficient steroid hormones. The term "Addisonian" is derived from the name of Thomas Addison, the British physician who first described the condition in 1855.

Etymology

The term "Addisonian" is derived from the name of Thomas Addison, a British physician who first described the condition in his 1855 publication, "On the Constitutional and Local Effects of Disease of the Supra-Renal Capsules".

Symptoms

The symptoms of Addisonian include fatigue, muscle weakness, loss of appetite, weight loss, low blood pressure, and darkening of the skin. These symptoms are often nonspecific and can be attributed to many different conditions, making diagnosis challenging.

Diagnosis

Diagnosis of Addisonian involves blood tests to measure levels of cortisol and aldosterone, hormones produced by the adrenal glands. An ACTH stimulation test may also be performed to assess the response of the adrenal glands to ACTH, a hormone that stimulates the production of cortisol.

Treatment

Treatment for Addisonian typically involves hormone replacement therapy to replace the deficient hormones. This usually includes taking a synthetic form of cortisol, such as hydrocortisone, and a synthetic form of aldosterone, such as fludrocortisone.

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