Acute uric acid nephropathy

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Acute Uric Acid Nephropathy (pronunciation: a-kyoot yoo-rik as-id neh-frop-uh-thee) is a medical condition that occurs when high levels of uric acid in the body lead to kidney damage or failure.

Etymology

The term "Acute Uric Acid Nephropathy" is derived from the following roots: "Acute" (Latin acutus meaning sharp or sudden), "Uric Acid" (from the Greek ouron meaning urine and acidus meaning sour or sharp), and "Nephropathy" (from the Greek nephros meaning kidney and pathos meaning suffering).

Definition

Acute Uric Acid Nephropathy is a form of kidney disease that results from the rapid production and deposition of uric acid crystals in the renal tubules. This condition is often associated with chemotherapy or radiation treatment for malignancies, which can cause a rapid turnover of nucleic acids.

Symptoms

Symptoms of Acute Uric Acid Nephropathy may include decreased urine output, flank pain, and blood in the urine (hematuria). In severe cases, it can lead to acute kidney failure.

Diagnosis

Diagnosis of Acute Uric Acid Nephropathy is typically made through blood and urine tests that measure the levels of uric acid and creatinine. Imaging tests such as ultrasound or CT scan may also be used to identify any blockages in the kidneys.

Treatment

Treatment for Acute Uric Acid Nephropathy typically involves measures to decrease the level of uric acid in the body. This can include medications such as allopurinol or rasburicase, as well as increased fluid intake to help flush out the uric acid.

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