Febrile neutrophilic dermatosis
Febrile neutrophilic dermatosis (pronunciation: feb-rile new-tro-fill-ic der-ma-toe-sis) is a rare skin condition, often associated with systemic diseases. It is also known as Sweet's syndrome, named after Dr. Robert Douglas Sweet who first described the condition in 1964.
Etymology
The term "Febrile neutrophilic dermatosis" is derived from the Latin "febris" meaning fever, "neutrophilic" referring to the type of white blood cell predominantly involved, and "dermatosis" indicating a skin disorder.
Symptoms
Febrile neutrophilic dermatosis is characterized by the sudden onset of fever, elevated white blood cell count (specifically neutrophils), and tender, red skin lesions that may be filled with pus (pustules). The skin lesions typically appear on the arms, neck, face, and upper trunk.
Causes
The exact cause of febrile neutrophilic dermatosis is unknown. However, it is often associated with underlying conditions such as cancer, inflammatory bowel disease, and rheumatoid arthritis. It can also occur as a reaction to certain medications.
Diagnosis
Diagnosis of febrile neutrophilic dermatosis is based on the clinical symptoms and a skin biopsy. The biopsy typically shows dense infiltration of the skin by neutrophils.
Treatment
Treatment typically involves systemic corticosteroids. Other treatments may include dapsone, colchicine, or potassium iodide. In cases where an underlying condition is identified, treating that condition can also help manage the symptoms of febrile neutrophilic dermatosis.
See also
External links
- Medical encyclopedia article on Febrile neutrophilic dermatosis
- Wikipedia's article - Febrile neutrophilic dermatosis
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