Acral erythema

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Acral Erythema

Acral erythema (pronunciation: ak-ral er-uh-thee-muh), also known as hand-foot syndrome or palmar-plantar erythrodysesthesia, is a skin condition characterized by redness, swelling, and pain on the palms of the hands and the soles of the feet.

Etymology

The term "acral" is derived from the Greek word "akron" meaning "extremity", and "erythema" comes from the Greek word "erythros" meaning "red".

Symptoms

The primary symptoms of acral erythema include:

  • Redness or erythema on the palms and soles
  • Swelling or edema
  • Pain and tenderness
  • Possible peeling of the skin

Causes

Acral erythema is often associated with chemotherapy treatment for cancer, particularly with drugs such as doxorubicin, fluorouracil, and cytarabine. It can also occur with other medical conditions such as HIV infection and hepatitis C virus infection.

Treatment

Treatment for acral erythema primarily involves managing the symptoms and may include:

  • Topical creams to soothe the skin
  • Pain relievers
  • Cold compresses
  • In severe cases, dose reduction or discontinuation of the causative chemotherapy drug may be necessary

See also

References

External links

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