Acemetacin

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Acemetacin (pronounced as: a-ce-me-ta-cin) is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is marketed under various trade names including Zaditen, Emflex, and Azelex.

Etymology

The term "Acemetacin" is derived from the chemical name N-(2,6-dichloro-m-tolyl)anthranilic acid, which is the chemical compound that makes up the drug. The name is a combination of "acet-" (from acetic acid), "-met-" (from methyl), and "-acin" (from anthranilic acid).

Pharmacology

Acemetacin works by inhibiting the production of prostaglandins, substances in the body that cause inflammation, pain, and fever. It does this by blocking the action of a substance in the body called cyclo-oxygenase (COX). COX is involved in the production of prostaglandins and as Acemetacin blocks the action of COX, it reduces the symptoms of pain and inflammation.

Side Effects

Like all NSAIDs, Acemetacin can cause side effects, although not everybody gets them. Common side effects include stomach upset, nausea, vomiting, heartburn, headache, dizziness, and rash. More serious side effects can include stomach or intestinal bleeding, which can be fatal.

Related Terms

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