From WikiMD

(uh-BEH-muh-SY-klib)A drug used to treat hormone-receptor positive (HR+), HER2-negative (HER2-) breast cancer that is advanced or has spread to other parts of the body.


  • It is used with an aromatase inhibitor in postmenopausal women who have not been treated with hormone therapy.
  • It is used with fulvestrant in women whose disease got worse after treatment with hormone therapy.
  • Abemaciclib is also used alone in men and women whose disease got worse after treatment with hormone therapy and previous chemotherapy.
  • It is also being studied in the treatment of other types of cancer.

Mechanism of action

Abemaciclib blocks certain proteins, which may help keep cancer cells from growing.

It is a type of cyclin-dependent kinase inhibitor.

Other names

Also called Verzenio.


WikiMD Resources - Abemaciclib

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