6-thioguanine

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6-Thioguanine

6-Thioguanine (pronounced as six-thio-gua-nine) is a medication used in the treatment of acute leukemia. It belongs to a class of drugs known as purine analogs.

Etymology

The term "6-Thioguanine" is derived from its chemical structure. The "6" refers to the position of the sulfur atom (thio) on the guanine molecule.

Usage

6-Thioguanine is used in the treatment of acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic myeloid leukemia (CML). It works by interfering with the growth of cancer cells, which helps slow down or stop the spread of cancer.

Side Effects

Common side effects of 6-Thioguanine include nausea, vomiting, diarrhea, and loss of appetite. More serious side effects can include low blood cell counts, liver problems, and skin rash.

Related Terms

  • Purine analogs: A class of drugs that 6-Thioguanine belongs to. These drugs mimic the structure of purine bases, which are part of DNA.
  • Leukemia: A type of cancer that 6-Thioguanine is used to treat. It affects the blood and bone marrow.
  • Guanine: One of the four main bases found in DNA and RNA. 6-Thioguanine is a derivative of guanine.

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