13-cis retinoic acid
13-cis Retinoic Acid
13-cis Retinoic Acid (pronunciation: 13-sis reh-tin-OH-ic acid), also known as Isotretinoin, is a medication primarily used to treat severe acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body.
Etymology
The term "retinoic acid" is derived from "retinol" which is a form of vitamin A. The "13-cis" refers to the specific chemical structure of the compound, indicating the position of a double bond in the molecule.
Related Terms
- Retinoid: A class of chemical compounds that are vitamers of vitamin A or are chemically related to it.
- Vitamin A: A group of unsaturated nutritional organic compounds that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids.
- Acne: A long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.
- Squamous-cell carcinoma: A form of skin cancer that arises from the squamous cells.
- Ichthyosis: A heterogeneous family of at least 28, generalized, mostly genetic skin disorders.
See Also
External links
- Medical encyclopedia article on 13-cis retinoic acid
- Wikipedia's article - 13-cis retinoic acid
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